|
KMID : 0665220070200030253
|
|
Korean Journal of Food and Nutrition
2007 Volume.20 No. 3 p.253 ~ p.258
|
|
|
Anti-Tumor Metastasis Activity by Extracts of Inonotus obliquus
|
|
Yoon Taek-Joon
Moon Won-Kook
Lee Kwang-Ho
|
|
|
Abstract
|
|
|
|
In experimental lung metastasis of colon26-M3.1 carcinoma cells, we found that the prophylactic or therapeutic admini-stration of Inonotus obliquus extracts significantly inhibited lung metastasis. In an in vitro cytotoxicity analysis, the extracts did not affect colon26-M3.1 cell growth at concentrations up to 1000 . Peritoneal macrophages that were stimulated with the extracts produced . These data suggest that Inonotus obliquus extract has antitumor activity to inhibit tumor metastasis, and its antitumor effects are partially associated with macrophages activation.
|
|
|
KEYWORD
|
|
|
Inonotus obliquus, metastasis, cytotoxicity, macrophage,
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|
|